Season 2

After Yumi makes a mistake that leads to their van crashing into the dumpster, Ami discovers an all-knowing Koi fish. Yumi becomes obsessed with it to avoid any more mistakes.

Kaz almost runs over a squirrel who left his home due to Eldwin Blair chopping down trees for toothpicks, Ami and Yumi decide to help the squirrel get his home back. Later on, Ami chains her and Yumi to the tree. Eldwin starts up the bulldozers and chases them through the forest until he surrounds them. Ami manages to convice Eldwin to save the tree.

After Yumi has an accident with the microwave, she thinks she's Ami, which leads to Ami and Kaz trying to get her back to normal in any way they could think of.

Ami and Yumi come back to their tour bus and find a note that Kaz left saying that he had to go to the hospital. Ami and Yumi go to one to visit him but the nurse kept saying that visiting hours aren't right now and they have to wait until the end of next month. Ami and Yumi keep trying to get in the hospital with the nurse chasing them. They get in a room with a guy who looks like Kaz but was taller. Eventually, The nurse catches them and throws them out. Ami and Yumi are sad but when they come back to the tour bus they find Kaz there and they find out that Kaz just went to the pet hospital for their cats.

Kaz enters Ami and Yumi's cats in a contest but turns out the cat contest isn't until October, so Kaz decides to enter the cats in a dog contest by pretending that they're dogs, but it backfires when the cats are told to speak and accidentally meow, and they and Kaz get chased out by the dogs.

Unlike Ami and Kaz, Yumi has never won a trophy before. Intent on winning one, she enters a tofu-dog eating contest. When she entered her first contest she lost. She challenged the champion to a rematch and if she won she got the champion's golden teeth, But if she loses, she and Ami must spit polish and clean his teeth for the rest of their lives. When the champion and Yumi get ready, Yumi starts out slow and the champion is winning but Kaz says mentions the baseball game they went to and Ami starts playing baseball. Yumi starts eating the Tofu-dogs fast and ends up winning the champion's gold teeth.

When Yumi's midnight hunger strikes she wants a Pink Palace cheeseburger so Yumi convinces Ami to drive her to a Pink Palace location. They end up going everywhere because the other locations get into trouble.

When getting attacked by fans after shows. Kaz hires them a body guard. When the body guard becomes too protective about his clients things start to go wrong.

Kaz writes a song, but Ami and Yumi don't like it, but hides those feelings not to disappoint Kaz.

Yumi's hands get RSI while signing autographs and can't use them, so Ami decides to help Yumi out. Yumi then takes advantage of Ami.

Ami's tired about not having the group being very clean. So Ami is obsessed in cleaning their trailer. But she now can't find her drum sticks so can she find them?

A magician named Dr. Mysto tries to hypnotise Yumi and cure her of nail biting. He hypnotises Kaz by mistake.

Yumi and Kaz accidentally sell Ami's diary to an auction, the diary is then bought by Harmony so then Ami and Yumi must become Harmony's best friend in order to get the diary back.

Yumi is tired of Ami always waking her up early, so Yumi sets Ami's clock backwards by 5 seconds. The clock affects Ami as she loses her sense of timing.

Yumi is tired of Ami using her stuff without her permission, so Yumi gets a security system that attacks whoever comes into her room. But, the security system soon targets Yumi. Can she find a way to stop it?

Kaz has a party in a hotel room and doesn't invite Ami and Yumi, now the girls try to sneak into the party.

Ami takes Yumi outside in the wild for some fresh air after she had been in a room for almost a week. Then, Ami gets kidnapped by Bigfoot. Can Yumi save her friend?

Ami and Yumi end up in prison after Kaz mistakes them for crooks.

Ami and Yumi are transported to the year 3000 where they discover the whole world is dedicated to them.

When Kaz is too short to go on a ride, Ami and Yumi must disguise him(And themselves too) so he can go on the ride. Can they get him on the ride? The name of the episode is a reference to "The right stuff".

Kaz is sick of being bald so he gets some hair growing liquid to grow his hair back. But suddenly, something scary happens! He becomes a Werewolf! He chases the cats around the bus.

Kaz books a ski trip for him, Ami and Yumi. Yumi wasn't a good skier so Ami signed up Yumi for ski school so she could get better But Yumi gets mad and lies to Ami and says that she passed. Ami finds out she didn't and Yumi said there were monkeys and little kids in the class. They start fighting and then start rolling down the hill. Meanwhile, Kaz is trying to skate across a frozen lake. While rolling down the hill, Ami and Yumi crash into the cabin and break all the bones in their body. In the end, Kaz uses Ami and Yumi as skis to ride down the mountain. The name is a reference to Seasick.

Fed up with the cats scratching up his stuff, Kaz tries to build Jang Keng and Tekerai a scratching post. The name puns Law &Order.

Chad, The good card game player of Stu-Pi-Doh comes back and has a new girlfriend named Janice. Ami and Yumi start to like Chad again and they start getting Jealous of Janice and they start to follow them everywhere to see what they do together. While following them and getting information of what Janice likes Ami and Yumi change to try to be more like Janice so Chad will like them again. They start dressing and acting like her. Chad falls for them and Janice gets sad and runs off. After hanging out with Ami and Yumi Chad starts to not like them. Later on, Janice comes back and tells Chad that she joined a rock band and she had hair like Ami's. Chad said that it ruled she was in a band. Ami and Yumi get mad and just keeping saying that they rule until the end of the episode.

When Kaz goes out and buys and a dog that looks just like him things start going crazy! When big time company owners come Kaz isn't there but Domo is! So can the girls get back before the company owners leave?

Yumi gets fed up with Ami and Kaz giving her all the hard work, so she wishes that there was no such thing as Puffy AmiYumi. Her wish came true, but Ami and Kaz are now having a hard life, and Yumi realizes how miserable she is without them.

Kaz, had it with Jang Keng and Tekirai, tries to frame them for various crimes. The name puns Cat Food.

Ami and Yumi are visited by an old friend named Atchan who thinks he's a superhero. Can Atchan help Yumi when she, Ami and Kaz are kidnapped by the giant snake monster Sunikura?

Ami's bad attempt at and album cover is discovered by an art critic who suggests to Ami that she should become an artist.

After breaking Yumi's new guitar, Ami tries to convince Yumi and Kaz that she saw a unicorn. This is the only episode where no dialogue is heard in this episode.

Kaz enters the cats into a racing contest, much to Ami and Yumi's disapproval.

Ami thinks Yumi and Kaz are dangerous drivers, so she makes them take driving classes.

Ami and Yumi compete with each other to complete a world record.

Ami and Yumi tried to save lobsters from a seafood restaurant.

Kaz is tired of how Ami and Yumi are playing, so he seeks the help of phantom rocker, Johnny Ghost. Ami and Yumi then get trapped in his haunted mansion.

Ami adopts a hunk of fungus that comes from their shower.

Ami, Yumi and Kaz compete against Axel and Rod Skidmark in a soap box derby.

The Talent Suckers seek a job in order to pay off some debts.

Ami and Yumi become slaves in a country.